上海科技大学人力资源管理
ShanghaiTech University Human Resources
Chao Zhong    Assistant Professor、PI
InstituteSchool of Physical Science and Technology
Research AreaBiologically Inspired Materials and Nanotechnology, Synthetic Biology
Contact Info.zhongchao@@shanghaitech.edu.cn
 
 Biography 
2014-now Assistent Professor、PI, School of Physical Science and Technology, ShanghaiTech University2012-2014  Postdoc, Dep. of EECS and Dep. of Biological Eng. , Synthetic Biology Center, MIT,USA  2009-2011  Postdoc, MSE, University of Washington, Seattle, USA 2004-2009  Ph. D.  BME, Fiber science, and Materials Science,Cornell University, USA 2001-2004  Master degree,  MSE,BUCT, Beijing, China1997-2001  Bachelor, MSE,Tianjin University, Tianjin, China
 Research Interests 
Our lab, the Integrative Bio-inspired Molecular Engineering (IBME) laboratory, aims to apply biologically inspired engineering principles to create novel materials, bionanotechnology, molecular (cellular) machines to address important yet unmet needs in our society. We are particularly interested in gearing our research towards practical applications in health care, environment as well as many other important technical fields. To these ends, we leverage and integrate various emerging techniques and/or advanced tools from synthetic biology, materials science, protein engineering, and modern micro/nanofabrication into our research.
 Selected Publications 
1.X. Mao, K. Li, M. Liu, X. Wang, T. Zhao, B. An, M. Cui, Y. Li, J. Pu, J. Li, L. Wang, T. K. Lu, C. Fan*, and C. Zhong*. Directing Curli Polymerization with DNA Origami Nucleators. Nature communications 2019, In press.DOI: 10.1038/s41467-019-09369-6.
2.M. Cui#,Q. Qi#, T. Gurry#, T. Zhao,B. An , J. Pu, X. Gui, A. Cheng, S. Zhang, D. Xun, M. Becce, F. Vangosa, C. Liu, T. K. Lu,C. Zhong*Genetic Design of Multi-domain Functional Amyloids: Insights into Self-assembly and Functional Properties, Chemical Science, In press.DOI: 10.1039/C9SC00208A.
3.C. Zhang#, J. Huang#, J. Zhang#, S. Liu, M. Cui, B. An, X. Wang, J. Pu, T. Zhao, C. Fan, T. K.Lu, C. Zhong*, Engineered Bacillus subtilis biofilms as living glues, Materials Today 2019, In press. DOI: 10.1016/j.mattod.2018.12.039.
4.J. Huang#, S. Liu#, C. Zhang#, X. Wang, J. Pu, F. Ba, S. Xue, H. Ye, T. Zhao, K. Li, Y. Wang, J. Zhang, L. Wang, C. Fan, T. K. Lu, C. Zhong*, Programmable and Printable Bacillus subtilis Biofilms as Engineered Living Materials. Nature Chemical Biology 2019, 15, 34–41.
5.X. Wang#, J. Pu#, B. An#, Y. Li,Y. Shang, Z. Ning, Y. Liu, F. Ba,J. Zhang,C. Zhong*,Programming cells for dynamic assembly of inorganic nano-objects with spatiotemporal control. Advanced Materials2018, 30, 1705968. (Inside back cover & video abstract highlight)
6.C. Zhang#, Y. Li#,  H. Wang,  S. HeY. Xu,  C. Zhong*  and  T. Li*, Adhesive bacterial amyloid nanofiber-mediated growth of metal–organic frameworks on diverse polymeric substrates. Chemical Science 2018, 9, 5672–5678. 
7.Y. Wang#, J. Hua#, B. An#, T. K. Lu*, C. Zhong*, Emerging Paradigms for Synthetic Design of Functional Amyloids, Journal of Molecular Biology 2018 in press, (Invited review in theme issue “functional amyloids”).
8.L. Jiang, X. Song, Y. Li, Q. Xu, J. Pu, H. Huang*, and C. Zhong*, Programming integrative extracellular and intracellular biocatalysis for rapid, robust, and recyclable synthesis of trehalose. ACS Catalysis 2018, 8, 1837−1842.
9.B. An#,X. Wang#,M. Cui#,X. GuiX. MaoY. LiuK. LiC. ChuJ. PuS. RenY. WangG. ZhongT. K. LuC. Liu, and C. Zhong*, Diverse supramolecular nanofiber networks assembled by functional low-complexity domains.ACS Nano 2017, 11 (7), 6985–6995.
10.M. Cui#, S. Ren#, S. Wei#, C. Sun, C. Zhong*, Natural and bio-inspired underwater adhesives: current progress and new perspectives. APL Materials 2017, 5, 116102. (Invited review).
11.X. Y. Wang #, Y. F. Li #,C. Zhong*, Amyloid-directed assembly of nanostructures and functional devices for bionanoelectronics.Journal of Materials Chemistry B. 2015, 3, 4953-4958.(Invited review).


  Before Joining ShanghaiTech
12.C. Zhong, T. K. Lu et al, Strong underwater adhesives made by self-assembling multi-protein nanofibres.Nature Nanotechnology 2014, 10, 858-866.(Highlighted in MIT News, the Scientist, Science Daily, Materials Today, MRS website and others) 
13.C. Zhong, Y. X. Deng, A. Kapetanovic, M. Rolandi, A polysaccharide bioprotonic field-effect transistor.NatureCommunications 2011, 2, 476.(Highlighted by MIT Tech Review, IEEE Spectrum, MRS website and others).
14.C. Zhong, A.Kapetanovic, Y. X. Deng, M. Rolandi, A chitin nanofiber ink for airbrushing, replica molding and microcontact printing of self-assembled marco-, micro- and nanostructures. Advanced Materials 2011, 23, 4776-4781.(Inside cover feature).
15.C. Zhong, C.C.Chu, Biomimetic mineralization of acid polysaccharide-based hydrogels: Towards porous 3-dimensional bone-like biocomposites.Journal of Materials Chemistry 2012, 22, 6080-6087.(Highlighted in Biomimetic Materials Collection on RSC Biomaterials Science Blog).
16.C. Zhong, C. C. Chu et al., Synthesis, characterization and cytotoxicity of photo-crosslinked maleic chitosan-PEGDA hybrid hydrogels.Acta Biomaterialia, 2010, 6, 3908-3918.
17.C. Zhong, A. Cooper, A. Kapetanovic, M. Zhang, M. Rolandi, A facile bottom-up route to self-assembled biogenic chitin nanofibers.Soft Matter 2010, 6, 5298-5301.
18.C. Zhong, C. C. Chu, On the origin of amorphous cores in biomimetic calcium carbonate spherulites: new insights into spherulitic crystallization.Crystal Growth and Design 2010, 10, 5043-5049.
19.C. Zhong, C. C. Chu, Acid polysaccharide-induced amorphous calcium carbonate (ACC) films: colloidal nanoparticle self-organization process.Langmuir 2009, 25, 3045–3049.
20.A. Y. Chen #,C. Zhong #, T. K. Lu, Engineering living functional materials. ACS Synthetic Biology 2015, 4, 8-11 (Invited Perspective paper).