上海科技大学人力资源管理
ShanghaiTech University Human Resources
Michael Levitt    Distinguished Adjunct Professor
Institute SIAIS
Stanford University
Research Area Computaional Biology
Contact Info. mlevitt@@shanghaitech.edu.cn
 
  Biography  
964-1967 B.Sc. Special Degree in Physics, King's College, London, UK.
1968-1971 Ph.D. in Biophysics, MRC Laboratory of Molecular Biology and Cambridge University, Cambridge, UK.
1972-1974 EMBO Postdoctoral Fellow with Shneior Lifson, Weizmann Institute, Rehovot, Israel
1974 - 1979 Staff Scientist, MRC Laboratory Molecular Biology, Cambridge, England.
1977 - 1979 Visiting Scientist with Francis Crick, Salk Institute, La Jolla, California.
1979 - 1987 Associate & Full Professor of Chemical Physics, Department of Chemical Physics,Weizmann Institute, Israel. Chair from 1980-1983; Full Professor from 1984.
1987 - Professor of Structural Biology, Department of Structural Biology, Stanford University School of Medicine, Stanford. Chair from 1993 till 2004.
April 4,2018- Distinguished Professor-in-Residence , SIAIS, ShanghaiTech University
  Research Interests  
Methodology for Simulation of Biological Macromolecules; Predicting protein structure from sequence; Modeling and prediction of RNA structure; Mesoscale modeling of large macromolecular complexes; Combinatorial Homology Modeling; Protein Structure, Sequence & Function; Antibody Modeling and Humanized Antibody Therapeutics
  Selected Publications  

Chopra, G., Summa, C., Levitt,M.  Solvent Dramatically AffectsProtein Structure Refinement.  Proc.  Natl. Acad. Sci. USA, 105: 20239-20244(2008).

Chopra, G. Levitt, M.  Remarkable patterns of surface water orderingaround polarized buckminsterfullerene.  Proc.Natl. Acad. Sci. USA, 108: 14455-14460 (2011).

Sim, A. Y. L., Levitt, M.  Clustering to identify RNA conformationsconstrained by secondary structure.  Proc.Natl. Acad. Sci. USA, 108: 3590-3595 (2011).

Bernauer, J., Huang, X., Sim, A.Y. L., Levitt, M.  Fullydifferentiable coarse-grained and all-atom knowledge-based potentials for RNAstructure evaluation. RNA 17: 1066-1075(2011).

Bray, J. K., Weiss, D. R., Levitt, M.  Optimized Torsion-Angle Normal ModesReproduce Conformational Changes More Accurately Than Cartesian Modes.  Biophysical J., 101: 2966-9(2011).

Minary, P., Levitt, M.  Training-Free Atomistic Prediction ofNucleosome Occupancy.  Proc. Natl.Acad. Sci. USA,  111: 6293-6298 (2014).

Silva, D.A., Weiss,D.R., Avila, F.P., Da, T.T., Levitt, M., Wang, D., Huang, X.  Millisecond dynamics of RNA polymerase II translocation at atomicresolution.  Proc. Natl. Acad.Sci. USA, 111, 7665-7670 (2014).

Levitt, M.  Birth and Future of Multiscale Modeling forMacromolecular Systems (Nobel Lecture). Angew. Chem. Int. Ed. doi:10.1002/anie.201403691 (2014).

Kalisman, N., Adams C. M., Levitt,M.  Subunit Order of EukaryoticTRiC/CCT Chaperonin by Cross-linking, Mass Spectrometry and CombinatorialHomology Modeling.  Proc. Natl.Acad. Sci. USA, 109: 2884-2889 (2012).

Brunger, A. T., Adams, P. D.,Fromme, P., Fromme, R., Levitt, M., Schröder, G. F.  Improving the Accuracy of MacromolecularStructure Refinement at 7 Å Resolution.  Structure 20: 957-966 (2012).

Zhang, J., Minary, P., Levitt,M.  Multi-scale Natural Moves RefineMacromolecules Using Single-particle Electron Microscopy Projection Images. Proc. Natl. Acad. Sci. USA 109:9845-50 (2012).

Kalisman, N., Schröder, G. F., Levitt,M.  The Crystal Structures of theEukaryotic Chaperonin CCT Reveal its Functional Partitioning.  Structure 21: 540-9 (2013).

Murakami, K., Elmlund, H.,Kalisman, N., Bushnell, D. A., Adams, C. M., Azubel, M., Elmlund, D.,Levi-Kalisman, Y., Liu, X., Gibbons, B. J., Levitt, M., Kornberg, R. D.  Architecture of an RNA polymerase IItranscription pre-initiation complex.  Science 342: 1238724 (2013).