上海科技大学人力资源管理
ShanghaiTech University Human Resources
Guang Yang    Distinguished Adjunct Professor
InstituteSIAIS
Research Areabiochemistry
Contact Info.yangguang@@shanghaitech.edu.cn
 
 Research Interests 
Phenotypic cellular model design; Therapeutic antibody and its target discovery; HTS screening platform technology
 Selected Publications 
                                        1. Pyridine-derived γ-secretase Modulators. Wan Z.; Hall A.; Sang Y.; Xiang JN.; Yang E.; Smith B.; Harrison DC.; Yang G.; Yu H.; Price HS.; Wang J.; Hawkins J.; Lau LF.; Johnson MR.; Li T.; Zhao W.; Mitchell WL.; Su X.; Zhang X.; Zhou Y.; Jin Y.; Tong Z.; Cheng Z.; Hussain I.; Elliott JD.; Matsuoka Y. Bioorg. Med. Chem. Lett. 2011; 21(16): 4832-5.
2. Yang, G. & Bu, H.-Z. “Toxicology of Chiral Drugs” (2011) in “Chiral Drugs: Chemistry and Biological Action” Wiley, ISBN: 978-0-470-58720-1, Chapter 11.
3. Combination of Virtual Screening and High Throughput Gene Profiling for Identification of LXR Modulators. Cheng, J.-F.; Zapf, J.; Takedomi, K.; Fukushima, C.; Ogiku, T.; Zhang, S.-H.; Yang, G.; Sakurai, N.; Barbosa, M.; Jack, R.; Xu, K. J. Med. Chem. 2008; 51(7): 2057-61.
4. Highly Potent Inhibitors of Methionine Aminopeptidase-2 Based on a 1,2,4-Triazole Pharmacophore. Marino, J.P.; Fisher, P.W.; Hofmann, G.A.; Kirkpatrick, R.B.; Janson, C.A.; Johnson, R.K.; Ma, C.; Mattern, M.; Meek, T.D.; Ryan, M.D.; Schulz, C.; Smith, W.W.; Tew, D.G.; Tomazek, T.A.; Veber, D.F.; Xiong, W.C.; Yamamoto, Y.; Yamashita, K.; Yang, G.; Thompson, S.K. J. Med. Chem. 2007; 50(16): 3777-85.