上海科技大学人力资源管理
ShanghaiTech University Human Resources

Jia Liu    Research Associate Professor, PI

Institute

Shanghai Institute for Advanced Immunochemical Studies

Research Area

Macromolecule Drug Delivery

Contact Info.

liujia@@shanghaitech.edu.cn

  

  

  

Biography

  

  

2006, B.Sc., Nankai   University, China

2012, Ph.D.,   University of Maryland, College Park

2012 to 2014,   Postdoctoral Fellow, The Scripps Research Institute, La Jolla, USA

2014.11 to 2018.08,   Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech   University, Research Associate Professor in Laboratory of ADC Chemistry

2018.08 to present,   Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech   University, PI of Laboratory of Macromolecule Drug Delivery, Research  Associate Professor

  

  

Research Interests

  

  

The research in Laboratory of Macromolecule Drug Delivery (LMDD) is focused on 1) understanding the mechanisms of cellular uptake of macromolecules and 2) developing  next-generation delivery technologies.

  

  

Selected Publications

  

  

1.  Li   B#, Zhou X-H# Yang P-Y, Zhu L, Zhong Y, Cai Z, Jiang B,   Cai X, Liu J*, Jiang X* (2019) Photoactivatable fluorogenic labeling via   turn‐on “click‐like” nitroso‐diene bioorthogonal reaction. Adv Sci, 1802039.

2.  Chen   J#, Yang Y-F#, Yang Y, Zou P,   Chen J, He Y, Shui S-L, Cui Y-R, Bai R, Liang Y-J, Hu Y, Jiang B, Lu L, Zhang X*, Liu J*, Xu J* (2017) AXL promotes   Zika virus infection in astrocytes by antagonizing type I interferon   signaling. Nat   Microbiol3,   302-309

3.  Mao   D#, Liang Y#, Liu Y, Zhou X, Ma J, Jiang B, Liu J* and Ma D* (2017) Acid   Labile acyclic cucurbit[n]uril molecular containers for controlled release. Angew Chem Int Ed, 56, 12614-12618.

4.  Chen   J#, Yang Y-F#,Chen J, Zhou X, Dong Z, Chen T, Yang Y, Zou   P, Jiang B, Hu Y, Lu L, Zhang X, Liu J*, Xu J*and Zhu T* (2017)   Zika virus infects renal proximal tubular epithelial cells with prolonged   persistency and cytopathic effects. Emerg   Microbes Infect, 6, e77.

5.  Liu J and Shui S-S (2016) Delivery methods for   site-specific nucleases: Achieving the full potential of therapeutic gene   editing. J Control Release 244,   83-97.

6.  Gaj T, Sirk JS, Shui SS and Liu J. (2016)   Genome editing technologies: principles and applications. CSH Perspect Biol, 8, pii: a023754.

7.  Liu J#*,   Gaj T#,   Yang Y, Wang N, Shui S, Kim S, Kanchiswamy CN, Kim JS, Barbas CF III. (2015)   Efficient delivery of nuclease proteins for genome editing in human stem   cells and primary cells. Nat Protoc, 10:1842-59.

8.  Liu J#*, Gaj T, Wallen MC,   Barbas CF III. (2015) Improved cell-penetrating zinc-finger nuclease proteins   for precision genome engineering. Mol   Ther- Nucleic Acids, 4, e232.