上海科技大学人力资源管理
ShanghaiTech University Human Resources
Houchao Tao    Research Associate Professor, PI
InstituteiHuman Institute
Research AreaMedicinal chemistry, Chemical biology
Contact Info.taohch@@shanghaitech.edu.cn
 
 Biography 
1999, B.S in Chemistry, Nankai University;2002, M.S in Organic chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences;2007, Ph.D in Chemistry, The Scripps Research Institute, La Jolla, CA, USA;2014, Research associate professor, iHuman Institute, ShanghaiTech University.
 Research Interests 
Chemical tool and methodology development for the structural and functional study of GPCR;Diagnostic and therapeutic agent development for specific GPCR targeting disease.
 Selected Publications 
                                        Tao, H., Lee, S.C., Moeller, A., Roy, R.S., Siu, F.-Y., Zimmermann, J., Stevens, R.C., Potter, C.S., Carragher, B., Zhang, Q.*, Engineered nanostructured β-sheet peptides protect integral membrane proteins as stable and functional single particles. Nature Methods, 2013, 10, 759-761.
Marcoux, J., Wang, S., Politis, A., Reading, E., Ma, J., Biggins, P., Zhou, M., Tao, H., Zhang, Q., Chang, G., Morgner, N.*, Robinson, C.V.*, Mass spectrometry reveals synergistic binding of nucleotides, lipids and drugs to a multidrug resistance efflux pump. Proc. Natl. Acad. Sci. USA 2013, 110, 9704-9709.
Tao, H., Fu, Y., Thompson A., Lee, S.C., Mahoney, N., Stevens, R.C., Zhang, Q.*, Synthesis and properties of dodecyl trehaloside detergents for membrane protein studies. Langmuir 2012, 28, 11173-11181.
Tao, H., Weng, Y., Zhuo, R., Chang, G., Urbatsch, I.L., Zhang, Q.*, Design and synthesis of selenazole-containing peptides for co-crystallization with P-glycoprotein. ChemBioChem. 2011, 12, 868-873.
Elliott I.G., Fuchs, J.R., Blagg, B.S.J., Ishikawa, H., Tao, H., Yuan, Z.-Q., Boger, D.L.*, Intramolecular Diels-Alder/1,3-dipolar cycloaddition cascade of 1,3,4-Oxadiazoles. J. Am. Chem. Soc. 2006, 128, 10589-10595.
Tao, H., Huang, I., and Boger, D.L.*, Multidrug resistance reversal activity of permethyl ningalin B amide derivatives. Bioorg. Med. Chem. Lett. 2004, 14, 5979-5981;
Yu, B.* and Tao, H., Glycosyl trifluoroacetimidates. 2. Synthesis of Dioscin and Xiebai Saponin I. J. Org. Chem. 2002, 67, 9099-9102.