上海科技大学人力资源管理
ShanghaiTech University Human Resources
Suwen Zhao    Assistant Professor, PI
InstituteiHuman Institute
Research AreaComputational Biology
Contact Info.zhaosw@@shanghaitech.edu.cn
 
 Biography 
2004B. En in Polymer Physics, University of Science and Technology of China, Hefei, China. Advisor: Qing-Xiang Guo
2009Ph.D in Chemistry, Columbia University, New York, United States. Advisor: Richard A. Friesner

2010-2014Postdoctoral Scholar, Department of Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, United States. Advisor: Matthew P. Jacobson

2014-presentResearch Associate Professor (PI) at iHuman Institute, Assistant Professor at School of Life Science and Technology, ShanghaiTech University, Shanghai, China
 Research Interests 
Predicting the full-length structures of multi-domain GPCRs
Discovering ligands for GPCRs and other proteins in cell signaling pathways
 Selected Publications 
                                        [1] S. Zhao, R. Kumar, A. Sakai, M. W. Vetting, B. M. Wood, S. Brown, J. B. Bonanno, B. S. Hillerich, R. D. Seidel, P. C. Babbitt, S. C. Almo, J. V. Sweedler, J. A. Gerlt, J. E. Cronan, and M. P. Jacobson, “Discovery of new enzymes and metabolic pathways by using structure and genome context”, Nature, 502, 698-702 (2013).
[2] S. Zhao, A. Sakai, X. Zhang, M. W. Vetting, R. Kumar, B. Hillerich, B. San Francisco, J. Solbiati, A. Steves, S. Brown, E. Akiva, A. Barber, R. D. Seidel, P. C. Babbitt, S. C. Almo, J. A. Gerlt and M. P. Jacobson, “Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networks”, eLife, e03275 (2014).
[3] M. P. Jacobson, C. Kalyanaraman, S. Zhao and B. Tian, “Leveraging structure for enzyme function prediction: methods, opportunities, and challenges”, Trends Biochem. Sci.,39(8), 363-71 (2014).
[4] R. Kumar, S. Zhao, A. Sakai, M. W. Vetting, B. M. Wood, S. C. Almo, J. V. Sweedler, J. A. Gerlt, J. E. Cronan, and M. P. Jacobson, “Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant, proline betaine”, mBio,5, (2014).
[5] S. Zhao, K. Zhu, J. Li, R. A. Friesner, “Progress in super long loop prediction”, Proteins, 79, 2920-2935 (2011).