1.Liu Q.＊, Zheng J.＊, Sun W., Huo Y.,Zhang L., Hao P., Wang H.#, Zhuang M#.A Proximity-tagging System to Identify Membrane Protein-Protein Interactions. Nature Methods 15, 715-722, 2018.(Research Highlight: Deane, C. PUP up the volume. Nat Chem Biol 14, 903, 2018)

2.Srinivasan S.R., Cesa L.C., Li X., Julien O., Zhuang M., Shao H., Chung J., Maillard I., Wells J.A., Duckett C.,Gestwicki J.E. Heat shock protein 70 (Hsp70) suppresses RIP-1 dependentapoptotic and necroptotic cascades. MolCancer Res 16(1):58–68, 2017.

3.Hill Z.B., Pollock S.B., ZhuangM., Wells J.A. Direct proximity tagging of small molecule protein targetsusing an engineered NEDD8 ligase. J. Am. Chem. Soc. 138(40): 13123-13126, 2016.

4. Julien O.＊, Zhuang M.＊, Witta A.P., O’Donoghue A.J.,Knudsen G.M., Craik C.S., Wells J.A.. Quantitative MS-based enzyme of caspasesreveals distinct protein substrate specificities, hierarchies, and cellularroles. PNAS 113(14) E2001-E2010, 2016. （＊equal contribution)

5. Li G., Ci W., Karmakar S., Chen K., Dhar R., Fan Z., Guo Z., Zhang J., KeY., Wang L., Zhuang M., Hu S., Li X., ZhouL., Li X., Calabrese M.F., Watson E.R., Prasad S.M., Rinker-Schaeffer C.,Eggener S.E., Stricker T., Tian Y., Schulman B.A., Liu J., White K.P.. SPOPpromotes tumorigenesis by acting as a key regulatory hub in kidney cancer. Cancer Cell 25, 1-14, 2014.
 
6. Zhuang M., Guan S., Wang H., BurlingameA.L., and Wells J.A.. Substrates of IAP ubiquitin ligases identified with adesigned orthogonal E3 ligase, the NEDDylator. MolCell 49, 273-282, 2013. (Faculty of 1000: http://f1000.com/prime/717975954)
 
7. Crawford E.D., Seaman J.E., Agard N., Hsu G.W., Julien O., Mahrus S., NguyenH., Shimbo K., Yoshihara H.A., Zhuang M.,Chalkley R.J., Wells J.A.. The DegraBase: a database of proteolysis in healthyand apoptotic human cells. Mol Cell Proteomics 12, 813-824, 2013.
 
8. Zhuang M., Calabrese M.F., Liu J.,Waddell M.B., Nourse A., Hammel M., Miller D.J., Walden H., Duda D.M., SeyedinS.N., Hoggard T., Harper J.W., White K.P., Schulman B.A.. Structures ofSPOP-substrate complexes: insights into molecular architectures of BTB-Cul3ubiquitin ligases. Mol Cell 36, 39-50,2009. (Faculty of 1000: http://f1000.com/prime/1166991)
 
9. Jin Y., Zhuang M. & HendershotL.M.. ERdj3, a luminal ER DnaJ homologue, binds directly to unfolded proteinsin the mammalian ER: identification of critical residues. Biochemistry 48, 41-49, 2009.
 
10. Huang D.T., Zhuang M., Ayrault O.,Schulman B.A.. Identification of conjugation specificity determinants unmasksvestigial preference for ubiquitin within the NEDD8 E2. NatStruct Mol Biol 15, 280-287, 2008.
 
11. Huang D.T., Hunt H.W., Zhuang M., OhiM.D., Holton J.M., Schulman B.A.. Basis for a ubiquitin-like protein thioesterswitch toggling E1-E2 affinity. Nature 445, 394-398, 2007. (Faculty of 1000: http://f1000.com/prime/1060912)
 
12. Huang D.T., Paydar A., Zhuang M.,Waddell M.B., Holton J.M., Schulman B.A.. Structural basis for recruitment ofUbc12 by an E2 binding domain in NEDD8's E1. MolCell 17, 341-350, 2005.